Sequential Complexity as a Descriptor for Musical Similarity

We propose string compressibility as a descriptor of temporal structure in audio, for the purpose of determining musical similarity. Our descriptors are based on computing track-wise compression rates of quantised audio features, using multiple temporal resolutions and quantisation granularities. To verify that our descriptors capture musically relevant information, we incorporate our descriptors into similarity rating prediction and song year prediction tasks. We base our evaluation on a dataset of 15500 track excerpts of Western popular music, for which we obtain 7800 web-sourced pairwise similarity ratings. To assess the agreement among similarity ratings, we perform an evaluation under controlled conditions, obtaining a rank correlation of 0.33 between intersected sets of ratings. Combined with bag-of-features descriptors, we obtain performance gains of 31.1% and 10.9% for similarity rating prediction and song year prediction. For both tasks, analysis of selected descriptors reveals that representing features at multiple time scales benefits prediction accuracy.Comment: 13 pages, 9 figures, 8 tables. Accepted versio

The Molonglo Galactic Plane Survey (MGPS-2): Compact Source Catalogue

We present the first data release from the second epoch Molonglo Galactic Plane Survey (MGPS-2). MGPS-2 was carried out with the Molonglo Observatory Synthesis Telescope at a frequency of 843 MHz and with a restoring beam of 45 arcsec x 45 arcsec cosec(dec), making it the highest resolution large scale radio survey of the southern Galactic plane. It covers the range |b| < 10 deg and 245 deg < l < 365 deg and is the Galactic counterpart to the Sydney University Molonglo Sky Survey (SUMSS) which covers the whole southern sky with dec 10 deg). In this paper we present the MGPS-2 compact source catalogue. The catalogue has 48,850 sources above a limiting peak brightness of 10 mJy/beam. Positions in the catalogue are accurate to 1 arcsec - 2 arcsec. A full catalogue including extended sources is in preparation. We have carried out an analysis of the compact source density across the Galactic plane and find that the source density is not statistically higher than the density expected from the extragalactic source density alone. We also present version 2.0 of the SUMSS image data and catalogue which are now available online. The data consists of 629 4.3 deg x 4.3 deg mosaic images covering the 8100 deg^2 of sky with dec 10 deg. The catalogue contains 210,412 radio sources to a limiting peak brightness of 6 mJy/beam at dec -50 deg. We describe the updates and improvements made to the SUMSS cataloguing process.Comment: 12 pages, 9 figures, to be published in MNRAS Note that Figures 8 and 9 are much lower resolution than in the published versio

Membrane-type 1 matrix metalloproteinase-mediated progelatinase A activation in non-tumorigenic and tumorigenic humaneratinocytes

Elevated expression of type IV collagenases (MMP-2 and MMP-9) has been strongly correlated with tumour progression and metastasis in various tumours. Here, we analysed expression and activation of these MMPs in non-tumourigenic HaCaT cells and the malignant HaCaT variant II-4 rt. In monolayer cultures, both cell types secreted latent MMP-2 (proMMP-2) in comparable amounts, while MMP-9 production was clearly higher in II-4 rt cells. Upon contact with fibrillar collagen type I the malignant II-4 rt cells, but not the HaCaT cells, gained the capability to activate proMMP-2. This process is shown to be membrane-associated and mediated by MT1-MMP. Surprisingly, all membrane preparations from either HaCaT cells or II-4 rt cells grown as monolayers, as well as within collagen gels, contained considerable amounts of active MT1-MMP. However, within collagen gels HaCaT cells showed significantly higher TIMP-2 levels compared to II-4 rt cells. This indicates that TIMP-2 might play a central role for MT1-MMP-mediated gelatinolytic activity. Indeed, collagen type I-induced MT1-MMP-mediated proMMP-2 activation by II-4 rt membranes could be completely abolished by an excess of TIMP-2. In conclusion, our data suggest that MT1-MMP-mediated proMMP-2 activation might be associated with malignant progression of epidermal tumour cells. © 2000 Cancer Research Campaig

Intonation in unaccompanied singing: Accuracy, drift, and a model of reference pitch memory

Copyright 2014 Acoustical Society of America. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the Acoustical Society of America. The following article appeared in J. Acoust. Soc. Am. 136, 401 (2014) and may be found at http://dx.doi.org/10.1121/1.4881915

Compact continuum source-finding for next generation radio surveys

We present a detailed analysis of four of the most widely used radio source finding packages in radio astronomy, and a program being developed for the Australian Square Kilometer Array Pathfinder (ASKAP) telescope. The four packages; SExtractor, SFind, IMSAD and Selavy are shown to produce source catalogues with high completeness and reliability. In this paper we analyse the small fraction (~1%) of cases in which these packages do not perform well. This small fraction of sources will be of concern for the next generation of radio surveys which will produce many thousands of sources on a daily basis, in particular for blind radio transients surveys. From our analysis we identify the ways in which the underlying source finding algorithms fail. We demonstrate a new source finding algorithm Aegean, based on the application of a Laplacian kernel, which can avoid these problems and can produce complete and reliable source catalogues for the next generation of radio surveys.Comment: 14 pages, 12 figures, accepted for publication in MNRA

Successful Treatment of a Panniculitis-Like Primary Cutaneous T-Cell Lymphoma of the α/β Type with Bexarotene

Subcutaneous panniculitis-like T-cell lymphoma (SPTL) of the α/β type is a rare subtype of non-Hodgkin's lymphoma of the skin. Although these tumors usually run an indolent course, disease-related morbidity is often severe. Clinical findings include subcutaneous tumors located on the extremities or trunk, often accompanied by systemic symptoms like fever or fatigue. Due to the low incidence of SPTL, no standardized therapy has been defined so far and there is currently no curative therapy available for this type of non-Hodgkin's lymphoma. By sharing our experience with bexarotene therapy, we present a safe and potentially improved treatment for patients with SPTL. In the case presented, bexarotene was able to induce remission even after recurrence of disease

Glassy timescale divergence and anomalous coarsening in a kinetically constrained spin chain

We analyse the out of equilibrium behavior of an Ising spin chain with an asymmetric kinetic constraint after a quench to a low temperature T. In the limit T\to 0, we provide an exact solution of the resulting coarsening process. The equilibration time exhibits a `glassy' divergence \teq=\exp(const/T^2) (popular as an alternative to the Vogel-Fulcher law), while the average domain length grows with a temperature dependent exponent, \dbar ~ t^{T\ln 2}. We show that the equilibration time \teq also sets the timescale for the linear response of the system at low temperatures.Comment: 4 pages, revtex, includes two eps figures. Proof of energy barrier hierarchy added. Version to be published in Phys Rev Let